##FastQC	0.11.2
>>Basic Statistics	pass
#Measure	Value
Filename	C68Y0ACXX_l03n01_34344-1.34100000035857.fastq.gz
File type	Conventional base calls
Encoding	Sanger / Illumina 1.9
Total Sequences	4672105
Sequences flagged as poor quality	0
Sequence length	101
%GC	41
>>END_MODULE
>>Per base sequence quality	pass
#Base	Mean	Median	Lower Quartile	Upper Quartile	10th Percentile	90th Percentile
1	32.678157276003	33.0	33.0	33.0	33.0	33.0
2	32.666239093513525	33.0	33.0	33.0	33.0	33.0
3	32.73218795382381	33.0	33.0	33.0	33.0	33.0
4	36.68179846129314	37.0	37.0	37.0	37.0	37.0
5	36.68862236614974	37.0	37.0	37.0	37.0	37.0
6	36.563212299381114	37.0	37.0	37.0	37.0	37.0
7	36.50629084748738	37.0	37.0	37.0	37.0	37.0
8	36.44919923674661	37.0	37.0	37.0	37.0	37.0
9	36.46048665430251	37.0	37.0	37.0	37.0	37.0
10-11	36.325693878883285	37.0	37.0	37.0	37.0	37.0
12-13	36.363916371742505	37.0	37.0	37.0	37.0	37.0
14-15	38.253343514325984	40.0	37.0	40.0	37.0	40.0
16-17	38.21719492605581	40.0	37.0	40.0	37.0	40.0
18-19	38.15552946691052	40.0	37.0	40.0	37.0	40.0
20-21	38.15568763972556	40.0	37.0	40.0	37.0	40.0
22-23	38.06152794083181	40.0	37.0	40.0	37.0	40.0
24-25	38.06646147721423	40.0	37.0	40.0	37.0	40.0
26-27	37.99914299871257	40.0	37.0	40.0	35.0	40.0
28-29	37.87110114177656	40.0	37.0	40.0	33.0	40.0
30-31	37.754946218032345	40.0	37.0	40.0	33.0	40.0
32-33	37.64613316695579	40.0	37.0	40.0	33.0	40.0
34-35	37.56094929373377	40.0	37.0	40.0	33.0	40.0
36-37	37.52460272189944	40.0	37.0	40.0	33.0	40.0
38-39	37.395675610886315	40.0	37.0	40.0	33.0	40.0
40-41	37.18873880188909	40.0	37.0	40.0	33.0	40.0
42-43	37.14436297985597	40.0	37.0	40.0	33.0	40.0
44-45	37.02921424069022	40.0	37.0	40.0	33.0	40.0
46-47	36.98432216313631	37.0	37.0	40.0	33.0	40.0
48-49	36.82646590776534	37.0	37.0	40.0	33.0	40.0
50-51	36.67394332961267	37.0	37.0	40.0	33.0	40.0
52-53	36.49744911554856	37.0	37.0	40.0	33.0	40.0
54-55	36.1704108747556	37.0	37.0	40.0	33.0	40.0
56-57	36.04175098804501	37.0	37.0	40.0	33.0	40.0
58-59	35.893252506097355	37.0	37.0	40.0	30.0	40.0
60-61	35.613588093589506	37.0	35.0	40.0	27.0	40.0
62-63	35.37555384564345	37.0	33.0	40.0	27.0	40.0
64-65	35.12923382501036	37.0	33.0	38.5	27.0	40.0
66-67	34.620483486565476	37.0	33.0	37.0	27.0	40.0
68-69	34.375725716780764	37.0	33.0	37.0	27.0	40.0
70-71	34.070405202794035	37.0	33.0	37.0	27.0	40.0
72-73	33.62346051726149	37.0	33.0	37.0	27.0	37.0
74-75	33.174214406568346	37.0	33.0	37.0	27.0	37.0
76-77	30.51503733327911	33.0	30.0	35.0	22.0	37.0
78-79	32.8700519359047	35.0	33.0	37.0	27.0	37.0
80-81	33.21795411276074	37.0	33.0	37.0	27.0	37.0
82-83	33.11514841811132	37.0	33.0	37.0	27.0	37.0
84-85	33.00358981658161	37.0	33.0	37.0	27.0	37.0
86-87	32.89037628649184	37.0	33.0	37.0	27.0	37.0
88-89	32.726978310633	37.0	33.0	37.0	27.0	37.0
90-91	32.622660663662316	35.0	33.0	37.0	27.0	37.0
92-93	32.44927468453727	33.0	33.0	37.0	22.0	37.0
94-95	32.31926176744743	33.0	33.0	37.0	22.0	37.0
96-97	32.1574301091264	33.0	33.0	37.0	22.0	37.0
98-99	32.02879002077222	33.0	33.0	37.0	22.0	37.0
100-101	30.43459575501835	33.0	30.0	35.0	18.5	37.0
>>END_MODULE
>>Per tile sequence quality	pass
#Tile	Base	Mean
2306	1	0.1368423447070768
2306	2	0.1781607604725366
2306	3	0.15351967663272603
2306	4	0.16093754607440758
2306	5	0.12369479020435392
2306	6	0.17217178282292167
2306	7	0.21981567769807242
2306	8	0.13985065346109593
2306	9	0.1729342115473571
2306	10-11	0.23844277449527596
2306	12-13	0.21514835283254286
2306	14-15	0.3975582464122951
2306	16-17	0.3710469327234023
2306	18-19	0.45596335128420407
2306	20-21	0.47173185551684327
2306	22-23	0.42778139585313113
2306	24-25	0.3703346192494976
2306	26-27	0.3437780397460841
2306	28-29	0.4455033955291512
2306	30-31	0.4540013291142344
2306	32-33	0.5648662049427742
2306	34-35	0.5269903003563243
2306	36-37	0.5168330216894361
2306	38-39	0.5207039598794125
2306	40-41	0.6707896683955283
2306	42-43	0.503364765302976
2306	44-45	0.5588366915705834
2306	46-47	0.47591252010832363
2306	48-49	0.5074391388948456
2306	50-51	0.5181953879026864
2306	52-53	0.6140636302862745
2306	54-55	0.6087497696345849
2306	56-57	0.6298584407394543
2306	58-59	0.5327349641737342
2306	60-61	0.618154779268167
2306	62-63	0.48399178071743165
2306	64-65	0.527459879385809
2306	66-67	0.6075617217700753
2306	68-69	0.6002903450242272
2306	70-71	0.5384380810642213
2306	72-73	0.4652608275577066
2306	74-75	0.5482109506994703
2306	76-77	0.20965525874022006
2306	78-79	0.46188374533287657
2306	80-81	0.6163351771734611
2306	82-83	0.5732074517206982
2306	84-85	0.6686021309239507
2306	86-87	0.8001861571590254
2306	88-89	0.5651136842026787
2306	90-91	0.6114396391632582
2306	92-93	0.6068176613864367
2306	94-95	0.6667436826458868
2306	96-97	0.8504560363676177
2306	98-99	0.7790515116401977
2306	100-101	0.562764749482703
2307	1	0.1356389684997481
2307	2	0.193302056885571
2307	3	0.136216398525292
2307	4	0.14293695881627855
2307	5	0.12903424073000735
2307	6	0.08296147735289594
2307	7	0.18365631232005342
2307	8	0.21336725188574945
2307	9	0.1299982657935317
2307	10-11	0.2124539678459385
2307	12-13	0.18746435326939093
2307	14-15	0.30820010852830393
2307	16-17	0.37703603156479204
2307	18-19	0.4389160406007093
2307	20-21	0.38628986953056454
2307	22-23	0.38635089780459
2307	24-25	0.350894207747281
2307	26-27	0.40385116919003394
2307	28-29	0.3174084350277724
2307	30-31	0.4041486944999235
2307	32-33	0.45709368076747836
2307	34-35	0.46316220364746385
2307	36-37	0.35467828731596285
2307	38-39	0.46764751124869264
2307	40-41	0.5231390960823106
2307	42-43	0.5850250795866643
2307	44-45	0.4770674040210281
2307	46-47	0.4116440396794374
2307	48-49	0.47462189975528446
2307	50-51	0.3806517866212573
2307	52-53	0.4576161012730324
2307	54-55	0.4968334472116638
2307	56-57	0.5608965655753906
2307	58-59	0.38676371778780805
2307	60-61	0.19717596462905362
2307	62-63	0.32554836442710666
2307	64-65	0.4593394335103156
2307	66-67	0.4758487889665801
2307	68-69	0.3608355442608868
2307	70-71	0.3660629716119601
2307	72-73	0.3165812961379615
2307	74-75	0.2702579308706561
2307	76-77	-0.007567199524221024
2307	78-79	0.40453057662980285
2307	80-81	0.4859164515906542
2307	82-83	0.3960303933953284
2307	84-85	0.3528597571365424
2307	86-87	0.37441269844816105
2307	88-89	0.5158345363688284
2307	90-91	0.4971174025815728
2307	92-93	0.4329554261076467
2307	94-95	0.40980639664064
2307	96-97	0.5772909545634164
2307	98-99	0.3778723610281318
2307	100-101	0.2302486956848746
2201	1	0.14894572476868717
2201	2	0.15256548253555025
2201	3	0.11354852018514094
2201	4	0.1387221610090421
2201	5	0.12516374148135867
2201	6	0.14277498317480308
2201	7	0.17452815056584114
2201	8	0.1279133150662659
2201	9	0.13320514294998986
2201	10-11	0.169390308815899
2201	12-13	0.12548641524102777
2201	14-15	0.2754878103223035
2201	16-17	0.24177685796528436
2201	18-19	0.3252196004862
2201	20-21	0.2660653461547824
2201	22-23	0.3796667731057539
2201	24-25	0.32102654389852603
2201	26-27	0.2331062628358893
2201	28-29	0.2787320903640307
2201	30-31	0.33883512151828654
2201	32-33	0.4467043851891077
2201	34-35	0.32829754099918773
2201	36-37	0.2558681688629889
2201	38-39	0.37930969360414934
2201	40-41	0.3637915633629305
2201	42-43	0.3189729069693641
2201	44-45	0.25846326656185425
2201	46-47	0.2580055563140675
2201	48-49	0.3619608213379095
2201	50-51	0.38455277009156674
2201	52-53	0.2948022344675749
2201	54-55	0.5108634823026321
2201	56-57	0.5065158622451094
2201	58-59	0.40913567356312797
2201	60-61	0.18522908797629611
2201	62-63	0.2722675066294471
2201	64-65	0.3093843990489802
2201	66-67	0.5396430304394002
2201	68-69	0.3362075986770563
2201	70-71	0.24259148511526263
2201	72-73	0.1675616183367694
2201	74-75	0.2001110084653277
2201	76-77	0.18340931345860056
2201	78-79	0.35364055278810014
2201	80-81	0.28353941686068396
2201	82-83	0.4350804714685168
2201	84-85	0.3013477187547622
2201	86-87	0.3898365078320509
2201	88-89	0.399906556785389
2201	90-91	0.4472589102335931
2201	92-93	0.31636545095675217
2201	94-95	0.3285062891850714
2201	96-97	0.3921727114619884
2201	98-99	0.25634520121315774
2201	100-101	0.35409790320005285
1101	1	0.091467242659661
1101	2	0.17485025851490832
1101	3	0.12274753135459804
1101	4	0.14009954662288493
1101	5	0.1041745500488176
1101	6	0.10232916735952813
1101	7	0.18922347166510178
1101	8	0.1850958697857692
1101	9	0.15474408567119724
1101	10-11	0.18034082518512662
1101	12-13	0.1712769684207487
1101	14-15	0.3209776242850282
1101	16-17	0.33197757131870276
1101	18-19	0.3963354031290933
1101	20-21	0.3571694801160561
1101	22-23	0.2925630722089494
1101	24-25	0.3084538401928185
1101	26-27	0.3102260232068801
1101	28-29	0.33782253467614964
1101	30-31	0.40959725484199083
1101	32-33	0.3715135661559259
1101	34-35	0.3637955952164518
1101	36-37	0.32117850166100936
1101	38-39	0.41262377962759444
1101	40-41	0.509621814119285
1101	42-43	0.474257797229626
1101	44-45	0.42628176442961063
1101	46-47	0.3549855330970004
1101	48-49	0.3647552901422273
1101	50-51	0.3231496412007502
1101	52-53	0.3448199780813681
1101	54-55	0.5213069523520133
1101	56-57	0.4606242606884834
1101	58-59	0.3996088566471485
1101	60-61	0.425741066419306
1101	62-63	0.3162301668482641
1101	64-65	0.32139111154830147
1101	66-67	0.4373880877903673
1101	68-69	0.4163094891237833
1101	70-71	0.3372816334999911
1101	72-73	0.12194910277351312
1101	74-75	0.1584129145504818
1101	76-77	-0.11896412044193028
1101	78-79	0.2918657102250748
1101	80-81	0.36502230179183215
1101	82-83	0.4370286601162121
1101	84-85	0.3689178060292875
1101	86-87	0.3327688354934466
1101	88-89	0.33657568951363004
1101	90-91	0.352429820330606
1101	92-93	0.25670721100294003
1101	94-95	0.3383681295887797
1101	96-97	0.27093751534994226
1101	98-99	0.2249498313941416
1101	100-101	0.3067729785352249
2304	1	0.11921815476262765
2304	2	0.17317767075991242
2304	3	0.12088661787909416
2304	4	0.1357637991027687
2304	5	0.09199721744325018
2304	6	0.14347886928354114
2304	7	0.15695593423137666
2304	8	0.12875775170235215
2304	9	0.09770480007470894
2304	10-11	0.12657170400657236
2304	12-13	0.1467956887421593
2304	14-15	0.13099846779272895
2304	16-17	0.19473493650355778
2304	18-19	0.33899128522229915
2304	20-21	0.26432489990685326
2304	22-23	0.22954577497031892
2304	24-25	0.1443205268624368
2304	26-27	0.10240220670635125
2304	28-29	0.25123632671560614
2304	30-31	0.2932066396339934
2304	32-33	0.30195434410074995
2304	34-35	0.28314058346470716
2304	36-37	0.24356489709607132
2304	38-39	0.2463103566852638
2304	40-41	0.437966537434761
2304	42-43	0.27044840413852
2304	44-45	0.2418890723187559
2304	46-47	0.38341686496415406
2304	48-49	0.3104371516089728
2304	50-51	0.27217242222901206
2304	52-53	0.2285485294309879
2304	54-55	0.3854453728205627
2304	56-57	0.37463016156105766
2304	58-59	0.303845759763675
2304	60-61	0.34230053638348323
2304	62-63	0.16808272802486357
2304	64-65	0.16858394112629327
2304	66-67	0.36930089191778137
2304	68-69	0.09948763993543963
2304	70-71	0.2489973020935352
2304	72-73	0.21420795807232906
2304	74-75	0.318282831485007
2304	76-77	0.14178028750775695
2304	78-79	0.43314511217919716
2304	80-81	0.5254008045704452
2304	82-83	0.41264792722059696
2304	84-85	0.5062992911637849
2304	86-87	0.6117856262742052
2304	88-89	0.5596501654201731
2304	90-91	0.4154593534211344
2304	92-93	0.30544048113544164
2304	94-95	0.4129057473854516
2304	96-97	0.4747325446149091
2304	98-99	0.42253543181803366
2304	100-101	0.49776717874142307
2202	1	0.07578126768500937
2202	2	0.11870872597872051
2202	3	0.0798125852151017
2202	4	0.07424452944091087
2202	5	0.08644247770399716
2202	6	0.07971022444811382
2202	7	0.08385894691981832
2202	8	0.09996572040214602
2202	9	0.07463667327456136
2202	10-11	0.1439277758365307
2202	12-13	0.08676720625255996
2202	14-15	0.12895300630807327
2202	16-17	0.14978745245679903
2202	18-19	0.21465325957206716
2202	20-21	0.1442650634158298
2202	22-23	0.10452869129228048
2202	24-25	0.1403125869504649
2202	26-27	0.09039994148334074
2202	28-29	0.21019933291952952
2202	30-31	0.12276132993962818
2202	32-33	0.14379994109170013
2202	34-35	0.17026228904096996
2202	36-37	0.09148813976717918
2202	38-39	0.1668632208547578
2202	40-41	0.2640858091321192
2202	42-43	0.2581994433350232
2202	44-45	0.301082053907642
2202	46-47	0.2546813188462238
2202	48-49	0.11790101054286595
2202	50-51	0.15029491874322076
2202	52-53	0.23645670938682173
2202	54-55	0.2651407308581142
2202	56-57	0.47733621616194455
2202	58-59	0.290008671171357
2202	60-61	0.278194107250215
2202	62-63	0.3144461581947837
2202	64-65	0.22555702597329486
2202	66-67	0.24238555717219867
2202	68-69	0.17761344414049773
2202	70-71	0.13650211823681246
2202	72-73	0.12918103855754026
2202	74-75	-0.02388193949920492
2202	76-77	-0.08705823320565642
2202	78-79	0.18404505852917197
2202	80-81	0.23492742675653489
2202	82-83	0.24848283200999077
2202	84-85	0.16163953987306456
2202	86-87	0.1464779964855083
2202	88-89	0.14395629911485486
2202	90-91	0.05166828171476112
2202	92-93	0.04834043184721537
2202	94-95	0.061387226497572556
2202	96-97	0.21406545970103252
2202	98-99	0.2902689438878312
2202	100-101	0.16329965881167752
1102	1	0.077627892872556
1102	2	0.14512281069264787
1102	3	0.11090775985758228
1102	4	0.08608863650320586
1102	5	0.0483086183622774
1102	6	0.06279681648035051
1102	7	0.023849399028229357
1102	8	0.01934216963569213
1102	9	0.07964354565807241
1102	10-11	0.1682090609197857
1102	12-13	0.07980183572092159
1102	14-15	0.10085125306336096
1102	16-17	0.09960751142290292
1102	18-19	0.1970610070041019
1102	20-21	0.21001619919523762
1102	22-23	0.10818259596025825
1102	24-25	0.06977950507991437
1102	26-27	0.04321211032363692
1102	28-29	0.10683488150360887
1102	30-31	0.18849948163568797
1102	32-33	0.12983890383393515
1102	34-35	0.12948649661843348
1102	36-37	0.1268590124024982
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1314	50-51	0.11308549153122271
1314	52-53	0.20172387003460557
1314	54-55	-3.0883964548467446
1314	56-57	-2.2646222181000155
1314	58-59	-0.3817213454812176
1314	60-61	0.2047250073128879
1314	62-63	0.3104853589964449
1314	64-65	-0.08564073401068839
1314	66-67	0.049763913624836675
1314	68-69	0.38005092921626726
1314	70-71	0.22479586564951148
1314	72-73	0.20605632987327027
1314	74-75	0.24745420784425676
1314	76-77	0.21292015598904257
1314	78-79	0.03372329475379132
1314	80-81	0.08116586927700808
1314	82-83	0.06589866457083104
1314	84-85	0.0729177994550696
1314	86-87	0.043828391840719405
1314	88-89	0.050180523863062376
1314	90-91	0.03755814637741395
1314	92-93	0.1307681620818002
1314	94-95	0.24649957140289303
1314	96-97	0.1819130391344288
1314	98-99	0.16601979554646817
1314	100-101	0.1813935597158398
1209	1	-0.014503322153430531
1209	2	0.032476901869735286
1209	3	0.00877799242203281
1209	4	-0.011484613834944923
1209	5	0.029391551723357168
1209	6	0.009707191029292517
1209	7	0.035476113706643275
1209	8	0.06049030488286178
1209	9	0.061811417896151966
1209	10-11	0.12925794574737637
1209	12-13	0.08961576380282565
1209	14-15	0.04597777397576408
1209	16-17	0.08986718803722482
1209	18-19	0.1479202122467953
1209	20-21	0.12076414354142173
1209	22-23	0.15886579079236185
1209	24-25	0.20686264427025947
1209	26-27	0.15218004619538306
1209	28-29	0.1517690877641371
1209	30-31	0.13723753335990807
1209	32-33	0.13480585428864345
1209	34-35	0.15717505658260222
1209	36-37	0.1467425529976083
1209	38-39	0.25865654260594795
1209	40-41	0.2970605490263054
1209	42-43	0.24704089401832618
1209	44-45	0.2776667197785301
1209	46-47	0.22059859318152775
1209	48-49	0.22120320208947675
1209	50-51	0.2267365805839887
1209	52-53	0.3180696609033262
1209	54-55	0.5414504192826612
1209	56-57	0.48984680358152843
1209	58-59	0.3043513253734247
1209	60-61	0.3042093176788754
1209	62-63	0.3460693524241947
1209	64-65	0.28424560416655
1209	66-67	-1.124241418981974
1209	68-69	-0.7423733388203573
1209	70-71	-0.04428737825505635
1209	72-73	0.3805638047991309
1209	74-75	0.36659647398336404
1209	76-77	0.5747492510658674
1209	78-79	0.2207448958276288
1209	80-81	0.20369709965944338
1209	82-83	-0.11899625906742273
1209	84-85	-0.20074468792487465
1209	86-87	0.10758415038620939
1209	88-89	0.18418012208926626
1209	90-91	0.3057393661422978
1209	92-93	0.275227947162044
1209	94-95	0.30475349409238106
1209	96-97	0.3694238758624593
1209	98-99	0.006748385581190064
1209	100-101	0.07233008754800352
1315	1	-0.00845235651510734
1315	2	0.05550383941676529
1315	3	0.017362090741571024
1315	4	-0.013001543857519948
1315	5	-0.016066888206410113
1315	6	-0.0053136266280944255
1315	7	-0.021959552207576394
1315	8	-0.014491987567602393
1315	9	-0.022084443653888286
1315	10-11	-0.01734947838103551
1315	12-13	-0.029802194561867168
1315	14-15	-0.06001430026552157
1315	16-17	-0.04285862084162062
1315	18-19	0.031597413149718534
1315	20-21	0.03176093310750616
1315	22-23	0.05940303684202064
1315	24-25	-0.038915685300842995
1315	26-27	0.03906893508427345
1315	28-29	0.047098809359319205
1315	30-31	0.09151037007924856
1315	32-33	-0.05438516652901626
1315	34-35	-0.9319712188124285
1315	36-37	-0.1839207025830234
1315	38-39	-0.022727355061469723
1315	40-41	0.03387103309954398
1315	42-43	0.07615511523729168
1315	44-45	0.05506832499548153
1315	46-47	0.04161023100446215
1315	48-49	0.08139943986223841
1315	50-51	0.07607106766700866
1315	52-53	0.09035513870619383
1315	54-55	0.3293187413293168
1315	56-57	0.23866210330563575
1315	58-59	-0.6886453137035744
1315	60-61	-0.15115772521051696
1315	62-63	0.04962079461130031
1315	64-65	0.0784669736172674
1315	66-67	-2.4889385847707857
1315	68-69	-1.8746016809322228
1315	70-71	-0.4888955548289218
1315	72-73	0.07909121889493775
1315	74-75	0.18948606515466793
1315	76-77	0.4426012199647893
1315	78-79	0.0451679206583222
1315	80-81	0.03257384909510819
1315	82-83	0.05172739280114769
1315	84-85	-0.0033639505283389326
1315	86-87	-0.1094512647128667
1315	88-89	-0.023456848063730718
1315	90-91	-0.09681839658657765
1315	92-93	-0.1046480498281781
1315	94-95	0.03769380008687051
1315	96-97	0.005068019328724915
1315	98-99	-0.15862552964328813
1315	100-101	-0.20987753723253277
1214	1	-0.009088739993643458
1214	2	0.011828838029494193
1214	3	0.006633955048023665
1214	4	0.0035005370480902798
1214	5	-0.035184820988540366
1214	6	-0.0070650647650793985
1214	7	-0.006923316704558147
1214	8	-0.005581908585675421
1214	9	0.027032830637217842
1214	10-11	-0.005961445900410922
1214	12-13	0.02407320265989199
1214	14-15	-0.042803461059413905
1214	16-17	0.02490245789984158
1214	18-19	0.14231446547756121
1214	20-21	0.06474354968446505
1214	22-23	0.003299823923754275
1214	24-25	-0.07800088590014553
1214	26-27	-0.10123263900521806
1214	28-29	-0.04012369771576374
1214	30-31	-0.05000155489717173
1214	32-33	-0.12462709908917446
1214	34-35	-0.09538004185221638
1214	36-37	-0.2880898089959203
1214	38-39	-0.4765356453894256
1214	40-41	-0.5311960478985469
1214	42-43	-0.7792650723216639
1214	44-45	-0.7743511448822531
1214	46-47	-0.8032052916265471
1214	48-49	-0.7860562618191338
1214	50-51	-0.8805040095577112
1214	52-53	-0.874608936539353
1214	54-55	-0.8336770968594678
1214	56-57	-1.0062898675431882
1214	58-59	-0.8717823501240431
1214	60-61	-0.9335511994905232
1214	62-63	-0.9200373893592513
1214	64-65	-0.8851524037757699
1214	66-67	-0.786954928665871
1214	68-69	-0.6823266388516842
1214	70-71	-0.7458870795315846
1214	72-73	-0.38318041235009304
1214	74-75	-0.4432435133000965
1214	76-77	-0.0649199904748805
1214	78-79	-0.48045201164288187
1214	80-81	-0.5087530916961853
1214	82-83	-0.5383823828309815
1214	84-85	-0.4423049637906473
1214	86-87	-0.33850653726525337
1214	88-89	-0.23746520128127457
1214	90-91	-0.19892062546770006
1214	92-93	-0.1231861553717124
1214	94-95	-0.016309714331498526
1214	96-97	-0.006537270795760719
1214	98-99	-0.07499348554658525
1214	100-101	-0.19147339391825113
1316	1	-0.029032038242867486
1316	2	0.015581759280365759
1316	3	0.009254645444606524
1316	4	-0.050273922374138635
1316	5	-0.039952622790103476
1316	6	0.017308140919510606
1316	7	-0.02459467582224306
1316	8	-0.039495454461608404
1316	9	-0.026912917652182955
1316	10-11	0.019148631877563105
1316	12-13	-0.71358336819074
1316	14-15	-0.37812283962329474
1316	16-17	-0.4930813829899634
1316	18-19	-0.08330262947602307
1316	20-21	-0.016654213240883564
1316	22-23	-0.1443687022884177
1316	24-25	-0.08515264182258875
1316	26-27	-0.30226368781995916
1316	28-29	-0.11860208578134745
1316	30-31	-0.03141861542800228
1316	32-33	-0.03529907673078014
1316	34-35	-0.023076461779183433
1316	36-37	0.034607373574971234
1316	38-39	-0.00791776426863322
1316	40-41	0.10123866594977926
1316	42-43	0.06486261736857557
1316	44-45	0.10554043354904508
1316	46-47	0.03054080787288882
1316	48-49	0.008814529376302005
1316	50-51	0.06015945925552302
1316	52-53	0.14522508755529628
1316	54-55	0.23892104311959628
1316	56-57	0.17483809080208346
1316	58-59	0.12358364338651029
1316	60-61	0.07263370701454619
1316	62-63	0.11110695545245619
1316	64-65	0.13987157719783028
1316	66-67	0.19027566643693916
1316	68-69	0.15033943870404443
1316	70-71	0.15624258100512378
1316	72-73	0.2939702754450977
1316	74-75	0.25317614756444584
1316	76-77	0.4062028539517186
1316	78-79	0.14844187632754569
1316	80-81	0.06958885335767917
1316	82-83	0.019468256682934282
1316	84-85	0.0011464927794264668
1316	86-87	-0.05015426272365886
1316	88-89	-0.055529681254981256
1316	90-91	0.009534573007059066
1316	92-93	-0.11946697565937825
1316	94-95	-0.011120422703697841
1316	96-97	-0.17011517191878767
1316	98-99	-0.2499758138149275
1316	100-101	-0.3041837037571149
1215	1	-0.019441245403996277
1215	2	0.004978859305388994
1215	3	-0.03452690421998028
1215	4	-0.046561209728636754
1215	5	-0.08610669197199172
1215	6	-0.14023035959016994
1215	7	-0.1475315490254019
1215	8	-0.16938851368799845
1215	9	-0.10095811111609976
1215	10-11	-0.11935248819276012
1215	12-13	-0.12570210174828844
1215	14-15	-0.21512781127055547
1215	16-17	-0.19106601940964651
1215	18-19	-0.14693261867207497
1215	20-21	-0.16350321433348824
1215	22-23	-0.17315424239426136
1215	24-25	-0.17605554210275187
1215	26-27	-0.24243510893587938
1215	28-29	-0.3010430760822089
1215	30-31	-0.13580470549752022
1215	32-33	-0.18212003791590803
1215	34-35	-0.04638792525634727
1215	36-37	-0.16303162806698168
1215	38-39	-0.07594048155311839
1215	40-41	-0.01786284385617165
1215	42-43	-0.1103642960594442
1215	44-45	-0.141332258404141
1215	46-47	-0.8598548180541528
1215	48-49	-0.36391690858645376
1215	50-51	-0.2024768108797943
1215	52-53	-0.17051037442030292
1215	54-55	0.060680316508317844
1215	56-57	0.03929680232446486
1215	58-59	0.031611793164636026
1215	60-61	-0.6500191810577718
1215	62-63	-0.2589450499922492
1215	64-65	-0.07773756098893614
1215	66-67	-0.06921250415556557
1215	68-69	0.024983694299812953
1215	70-71	-0.02859725199147789
1215	72-73	0.17139620430994995
1215	74-75	-0.05483212630647927
1215	76-77	0.20595804839226162
1215	78-79	-0.05824047234088425
1215	80-81	-0.126554114309819
1215	82-83	-0.06769427253960458
1215	84-85	-0.1281815718489412
1215	86-87	-0.20610192766698532
1215	88-89	-0.13977014692345335
1215	90-91	-0.030129878951996147
1215	92-93	-0.11260520973271326
1215	94-95	-0.06966870322790442
1215	96-97	-0.20547940840928192
1215	98-99	-0.22496631458096772
1215	100-101	-0.22150889496257875
1212	1	-0.11485580106604942
1212	2	-0.08223447816961738
1212	3	-0.18762247876563265
1212	4	-0.39050229697267724
1212	5	-0.20743194670596665
1212	6	-0.22862143011828806
1212	7	-0.20578939382517802
1212	8	-0.20353237584031092
1212	9	-0.16677157679551868
1212	10-11	-0.16007735581344917
1212	12-13	-0.1685993038168121
1212	14-15	-0.4082836811896513
1212	16-17	-1.1603003297283863
1212	18-19	-0.43449743371686367
1212	20-21	-0.39546993396386654
1212	22-23	-0.42799228015099544
1212	24-25	-0.5419417293923132
1212	26-27	-0.47540450809736967
1212	28-29	-0.5861892092631678
1212	30-31	-0.39205919493969077
1212	32-33	-0.506047016301558
1212	34-35	-0.7222282638624122
1212	36-37	-0.5587158035308875
1212	38-39	-0.5368154832279757
1212	40-41	-0.4278221280062411
1212	42-43	-0.53955298645608
1212	44-45	-0.39660418706197476
1212	46-47	-0.2880315661261008
1212	48-49	-0.27372935652280717
1212	50-51	-0.38167770528779243
1212	52-53	-0.273056719434301
1212	54-55	-0.03247285116692211
1212	56-57	-0.3539107145622111
1212	58-59	-0.3971025747987085
1212	60-61	-0.394670035220102
1212	62-63	-0.5290774815917771
1212	64-65	-0.4171740506193444
1212	66-67	-0.3486104152209819
1212	68-69	-0.3706537995440513
1212	70-71	-0.6159208442837851
1212	72-73	-0.1561074787483463
1212	74-75	-0.20982284594731482
1212	76-77	-0.11390245128142595
1212	78-79	-0.253506012428538
1212	80-81	-0.244849638969157
1212	82-83	-0.1980919995338084
1212	84-85	-0.3022513484013558
1212	86-87	-0.34225058310560996
1212	88-89	-0.3065513815126977
1212	90-91	-0.3358962671724868
1212	92-93	-0.2757576760091993
1212	94-95	-0.3169362301898815
1212	96-97	-0.45358713304397114
1212	98-99	-0.47313955279967956
1212	100-101	-0.4546388560208534
1213	1	-0.18753201785204254
1213	2	-0.14658955142539298
1213	3	-0.18226255672644243
1213	4	-0.2723265994058153
1213	5	-0.2685229273588874
1213	6	-0.35023562665713825
1213	7	-0.4229954080869831
1213	8	-0.5341361764172845
1213	9	-0.3891369770917805
1213	10-11	-2.3588107020409765
1213	12-13	-0.8352800434995515
1213	14-15	-1.1573745175210703
1213	16-17	-0.9760184169467081
1213	18-19	-0.872071998256196
1213	20-21	-0.8881210634361523
1213	22-23	-0.9438143203661866
1213	24-25	-0.9158711682442586
1213	26-27	-0.9851549426949617
1213	28-29	-1.1571412638337293
1213	30-31	-1.097904312097377
1213	32-33	-1.193397246286196
1213	34-35	-1.3020669448613162
1213	36-37	-1.3029593061061746
1213	38-39	-1.712213069347186
1213	40-41	-1.195028730184852
1213	42-43	-1.172676392626606
1213	44-45	-1.2535368885568516
1213	46-47	-1.1481838235127455
1213	48-49	-1.2713381369251096
1213	50-51	-1.1861010695989975
1213	52-53	-1.1638659565754708
1213	54-55	-1.0553091504495384
1213	56-57	-1.8066808613032066
1213	58-59	-1.367131739588352
1213	60-61	-1.3880021638459894
1213	62-63	-1.2843432071894796
1213	64-65	-1.3865871108161372
1213	66-67	-1.3897410477748977
1213	68-69	-1.364268960445429
1213	70-71	-1.5618308341678642
1213	72-73	-1.2344187304217797
1213	74-75	-1.278194348444135
1213	76-77	-0.9552913663347518
1213	78-79	-1.280035860982423
1213	80-81	-1.1858120002492072
1213	82-83	-1.2632255748573975
1213	84-85	-1.3270474777361088
1213	86-87	-1.481944527757637
1213	88-89	-1.3835263349862856
1213	90-91	-1.3075056037780826
1213	92-93	-1.4567760330983361
1213	94-95	-1.376312444557989
1213	96-97	-1.6012995201359814
1213	98-99	-1.606634858852253
1213	100-101	-1.5245228617362265
>>END_MODULE
>>Per sequence quality scores	pass
#Quality	Count
7	2.0
8	9.0
9	43.0
10	34.0
11	50.0
12	66.0
13	147.0
14	412.0
15	979.0
16	1867.0
17	3315.0
18	4901.0
19	6950.0
20	9454.0
21	11921.0
22	15448.0
23	19700.0
24	24420.0
25	31149.0
26	39812.0
27	52233.0
28	73571.0
29	102000.0
30	107459.0
31	109006.0
32	141595.0
33	198624.0
34	302431.0
35	524343.0
36	1016604.0
37	1508860.0
38	364495.0
39	205.0
>>END_MODULE
>>Per base sequence content	warn
#Base	G	A	T	C
1	36.06106554064758	24.943892341896884	23.93784542734109	15.057196690114441
2	28.875250021136083	23.91611489895882	33.58124442836794	13.627390651537155
3	37.0707069842266	19.100299183954252	27.419252652266398	16.409741179552753
4	27.954060072622127	19.156049806714176	34.502445532870155	18.38744458779355
5	33.56061133043885	18.00334110641777	32.138511441844734	16.297536121298645
6	26.894643848971718	19.40806124862348	37.45735594555345	16.239938956851354
7	31.96923014358624	21.497098203058364	29.13162268399362	17.402048969361775
8	27.82782065043487	28.645738912117768	26.404671984041457	17.121768453405906
9	31.783061382396156	23.83330426007121	25.78871836142381	18.59491599610882
10-11	25.002766418991012	28.854242359707243	28.82666378431135	17.31632743699039
12-13	23.98585862261229	27.05856353827664	28.808374383709268	20.147203455401794
14-15	22.956515318041866	27.513711699544423	29.594968434998787	19.934804547414924
16-17	23.137022819478588	27.1326093912701	30.422743067632258	19.307624721619057
18-19	21.184883473295226	27.43364072511213	31.567591053711336	19.813884747881307
20-21	22.48572002800452	27.53218411494781	31.17145533820637	18.8106405188413
22-23	21.3684087962196	29.876759862485763	29.83260411061583	18.92222723067881
24-25	21.38682670873193	27.151615813428855	31.133386342986725	20.32817113485249
26-27	21.317061581449902	27.327585745611454	29.596316863597888	21.75903580934076
28-29	21.964628363446455	28.88164970607467	29.363135032282024	19.790586898196853
30-31	20.45707448783792	28.207403301081634	30.486065702718584	20.849456508361865
32-33	20.395421335779055	29.22725409638696	29.779767363961213	20.597557203872775
34-35	20.6186718834444	29.38809166317966	31.066831759988272	18.92640469338767
36-37	20.47774958899383	28.484059852686315	31.036503940115633	20.001686618204218
38-39	22.258939594488382	29.35309193617156	29.24963570392618	19.138332765413875
40-41	20.87862868503332	30.458864468088247	28.97701696356273	19.685489883315707
42-43	20.89135816527162	29.386788596046998	30.526997680219626	19.19485555846176
44-45	20.53966072469527	28.26865057956936	30.755751253759993	20.435937441975373
46-47	21.885765832445696	28.10727254572865	29.499179534608356	20.507782087217297
48-49	20.825583192314657	29.592121761368574	30.12198525757295	19.46030978874382
50-51	21.991081467332783	28.45985365370246	29.75944918621707	19.789615692747688
52-53	20.585617054534552	28.178006897054413	28.866888177017902	22.36948787139313
54-55	22.063341398635337	28.434123560226908	29.73992960354061	19.762605437597138
56-57	20.870929956968304	28.361151534134933	29.60518273002818	21.162735778868587
58-59	20.782359448018788	28.327218786320397	29.962550584969154	20.927871180691664
60-61	21.747821175608127	28.664103276682972	29.87241785811703	19.715657689591872
62-63	20.561213568957843	28.61459296551252	29.811466146100894	21.01272731942875
64-65	21.937530416496358	28.462883659918337	29.68064591982	19.918940003765304
66-67	21.05768655379901	30.46371241623803	28.38117771437374	20.097423315589218
68-69	21.19654549582681	30.472274785452992	28.324091042072936	20.007088676647264
70-71	20.93982142031314	31.09915317670071	28.236499899799426	19.724525503186722
72-73	20.65939959694794	31.510192720976104	28.046482126273588	19.78392555580237
74-75	21.133270638294594	30.828572321767727	27.947448367595058	20.090708672342622
76-77	21.19338224873555	30.18026012193028	28.33214591387127	20.294211715462897
78-79	20.970906394145807	29.938499571934074	28.84559626174666	20.244997772173456
80-81	20.576015710978954	30.135069207555876	28.70506443166831	20.583850649796858
82-83	19.891458384014662	30.117226786113534	28.978907612158295	21.01240721771351
84-85	20.017968174881673	29.88372488784875	29.050015701282195	21.04829123598738
86-87	20.01566008410711	30.000901407630447	29.428164984574366	20.555273523688072
88-89	20.15832001012981	30.196324990048407	29.23331880865996	20.412036191161828
90-91	20.345158417131376	29.92151851121197	28.944436339051933	20.78888673260472
92-93	19.991091609731132	30.572792362768496	28.732931385051252	20.70318464244912
94-95	19.696462852282043	30.896224192682077	28.74507539707355	20.662237557962328
96-97	20.073187953108746	31.077140166814143	28.456484697818656	20.39318718225845
98-99	20.40651262089815	30.4621319526975	28.167364803314314	20.963990623090037
100-101	20.399414740702017	30.429832850809518	27.78070697670236	21.390045431786106
>>END_MODULE
>>Per sequence GC content	fail
#GC Content	Count
0	61.0
1	47.0
2	67.5
3	182.5
4	224.5
5	148.0
6	101.0
7	100.0
8	113.5
9	109.0
10	94.0
11	96.0
12	103.0
13	108.0
14	127.0
15	145.5
16	171.0
17	219.5
18	286.0
19	407.0
20	601.0
21	845.0
22	1244.0
23	1962.0
24	2981.5
25	4501.0
26	7100.5
27	10684.5
28	14734.0
29	19179.0
30	24433.0
31	30815.5
32	43433.5
33	65875.5
34	98209.5
35	137977.5
36	192071.0
37	258486.5
38	317462.5
39	340242.0
40	335818.5
41	314151.0
42	288147.5
43	285916.5
44	278137.0
45	256308.5
46	239650.5
47	211789.0
48	170143.5
49	139575.0
50	117392.5
51	98939.5
52	83585.5
53	68064.5
54	52615.5
55	39133.0
56	29221.5
57	21698.0
58	16865.5
59	13125.0
60	9894.5
61	7406.5
62	5472.5
63	3928.0
64	2811.0
65	1991.5
66	1366.0
67	942.0
68	677.0
69	500.5
70	341.5
71	230.5
72	170.5
73	112.0
74	73.0
75	51.5
76	37.5
77	30.5
78	23.0
79	13.0
80	10.5
81	7.0
82	3.0
83	4.0
84	3.0
85	1.0
86	1.0
87	2.0
88	1.0
89	0.0
90	1.0
91	1.5
92	0.5
93	0.0
94	0.0
95	0.0
96	0.0
97	0.0
98	0.0
99	0.0
100	0.0
>>END_MODULE
>>Per base N content	pass
#Base	N-Count
1	0.15864369486559057
2	0.0
3	0.0013484285991004056
4	0.011258308621060528
5	0.0
6	0.0
7	0.0
8	0.0
9	0.0
10-11	0.0
12-13	0.0
14-15	0.0
16-17	0.0
18-19	0.0
20-21	4.280725711429859E-5
22-23	1.4982539990004507E-4
24-25	0.0
26-27	0.0
28-29	0.0
30-31	0.0
32-33	0.0
34-35	0.0
36-37	7.27723370943076E-4
38-39	0.0017336939131290926
40-41	0.005736172453316011
42-43	0.0023758027698435715
44-45	0.0012521122705932337
46-47	0.0013163231562646814
48-49	0.003146333397900946
50-51	7.705306280573745E-4
52-53	0.014779205518711586
54-55	0.027257520967529626
56-57	0.029151742094837337
58-59	0.02148924307137789
60-61	0.03139912309333801
62-63	0.005671961567644563
64-65	0.010776726978524668
66-67	0.02899121488065872
68-69	0.027300328224643924
70-71	0.03152754486468091
72-73	0.03194491562154532
74-75	0.04021741805888352
76-77	0.01949870561556301
78-79	0.010947956006981863
80-81	0.01545341981826179
82-83	0.0074591645521665285
84-85	0.010958657821260438
86-87	0.03493072180526765
88-89	0.0159135978322405
90-91	0.021478541257099314
92-93	0.050298527109300835
94-95	0.05763997170440305
96-97	0.041469530329476756
98-99	0.03631125584720378
100-101	0.03631125584720378
>>END_MODULE
>>Sequence Length Distribution	pass
#Length	Count
101	4672105.0
>>END_MODULE
>>Sequence Duplication Levels	fail
#Total Deduplicated Percentage	45.9070604792119
#Duplication Level	Percentage of deduplicated	Percentage of total
1	90.87950288262704	41.72010835153472
2	4.116943784550315	3.779935746137336
3	1.2566114570486069	1.7306201447280294
4	0.750032965348271	1.3772723480658287
5	0.5161630231333837	1.1847763560058546
6	0.3366240180352865	0.9272051492820729
7	0.305615091567644	0.9820923344368999
8	0.17355089958942652	0.6373769314938748
9	0.17012531696838976	0.7028957893601666
>10	1.164356418107706	10.622274206694783
>50	0.1495989017941525	4.862466471493474
>100	0.14319141805671126	14.345400375826213
>500	0.028907021773288813	9.12952896219439
>1k	0.00858993834837422	5.437484163526567
>5k	1.4014741385463413E-4	0.4433284297744103
>10k+	4.6715637671161563E-5	2.1172342394453025
>>END_MODULE
>>Overrepresented sequences	fail
#Sequence	Count	Percentage	Possible Source
GATCGGAAGAGCACACGTCTGAACTCCAGTCACATTCAGAAATCTCGTAT	98725	2.1130732293045638	TruSeq Adapter, Index 13 (97% over 38bp)
GTGTTTGAGAGAGTAAAAAATTTAACACCCATAGTAGGCCTAAAAGCAGC	7730	0.16545004874676403	No Hit
TTGTGTTTGAGAGAGTAAAAAATTTAACACCCATAGTAGGCCTAAAAGCA	7191	0.15391349295446058	No Hit
TGTGTTTGAGAGAGTAAAAAATTTAACACCCATAGTAGGCCTAAAAGCAG	5751	0.12309226783216559	No Hit
>>END_MODULE
>>Adapter Content	pass
#Position	Illumina Universal Adapter	Illumina Small RNA Adapter	Nextera Transposase Sequence
1	0.0011771995706432112	0.0	0.0
2	0.0013270249705432562	0.0	0.0
3	0.001455446741886152	0.0	2.1403628557149293E-5
4	0.0015838685132290478	0.0	2.1403628557149293E-5
5	0.0018621156844719885	0.0	2.1403628557149293E-5
6	0.0020119410843720334	0.0	2.1403628557149293E-5
7	0.002397206398400721	0.0	2.1403628557149293E-5
8	0.0027182608267579604	0.0	2.1403628557149293E-5
9	0.0032533515406866927	0.0	2.1403628557149293E-5
10-11	0.005158274482272979	0.0	2.1403628557149293E-5
12-13	0.007245128266595036	0.0	2.1403628557149293E-5
14-15	0.00985637095056725	0.0	2.1403628557149293E-5
16-17	0.01227498097752512	0.0	2.1403628557149293E-5
18-19	0.015303594418361745	0.0	2.1403628557149293E-5
20-21	0.018963614901634274	0.0	2.1403628557149293E-5
22-23	0.023115918841721237	0.0	2.1403628557149293E-5
24-25	0.028113666109815597	0.0	2.1403628557149293E-5
26-27	0.0333040460349243	0.0	4.280725711429859E-5
28-29	0.038911796716897415	0.0	4.280725711429859E-5
30-31	0.05903120756061775	0.0	4.280725711429859E-5
32-33	0.0678388007118847	0.0	6.421088567144788E-5
34-35	0.07510533260703686	0.0	6.421088567144788E-5
36-37	0.08291765703039636	0.0	6.421088567144788E-5
38-39	0.09129717761052031	0.0	6.421088567144788E-5
40-41	0.10031880704735874	0.0	6.421088567144788E-5
42-43	0.10944745462698291	0.0	6.421088567144788E-5
44-45	0.11998874169137894	0.0	6.421088567144788E-5
46-47	0.13056213419861068	0.0	6.421088567144788E-5
48-49	0.14270869340479292	0.0	6.421088567144788E-5
50-51	0.1554545542105753	0.0	6.421088567144788E-5
52-53	0.16962375631540816	0.0	6.421088567144788E-5
54-55	0.18416752191999108	0.0	6.421088567144788E-5
56-57	0.2000383124951173	0.0	6.421088567144788E-5
58-59	0.2171719171551153	0.0	6.421088567144788E-5
60-61	0.23517236877167785	0.0	6.421088567144788E-5
62-63	0.25624424108619137	0.0	6.421088567144788E-5
64-65	0.2780438367716479	0.0	8.561451422859717E-5
66-67	0.30249748239819096	0.0	1.0701814278574647E-4
68-69	0.32913429813756323	0.0	1.0701814278574647E-4
70-71	0.35902446541762223	0.0	1.0701814278574647E-4
72-73	0.39059481753941744	0.0	1.0701814278574647E-4
74-75	0.42576097925881373	0.0	1.0701814278574647E-4
76-77	0.4636025945478537	0.0	1.0701814278574647E-4
78-79	0.5069128369332453	0.0	1.0701814278574647E-4
80-81	0.5542148560445452	0.0	1.0701814278574647E-4
82-83	0.6084730544369187	0.0	1.0701814278574647E-4
84-85	0.6646682812137141	0.0	1.1771995706432112E-4
86-87	0.7257649389300969	0.0	1.2842177134289576E-4
88-89	0.7925228563998454	0.0	1.2842177134289576E-4
>>END_MODULE
>>Kmer Content	fail
#Sequence	Count	PValue	Obs/Exp Max	Max Obs/Exp Position
TCGGAAG	16415	0.0	66.74205	3
CGGAAGA	16335	0.0	66.485344	4
GATCGGA	16555	0.0	66.32374	1
ATCGGAA	16800	0.0	65.24082	2
GAAGAGC	17185	0.0	63.164497	6
GGAAGAG	19675	0.0	55.339558	5
CGACGGG	160	0.0	50.52464	1
TTGTGTT	56035	0.0	45.324966	1
GCCGTCT	12340	0.0	43.544262	50-51
ATGCCGT	12355	0.0	43.483944	48-49
TCTCGTA	12480	0.0	43.073326	42-43
TCGTATG	12750	0.0	42.924934	44-45
CGTCTTC	12535	0.0	42.811157	52-53
TATGCCG	12530	0.0	42.743942	48-49
TGCCGTC	12385	0.0	42.73391	50-51
CGTATGC	12580	0.0	42.71755	46-47
AATCTCG	12495	0.0	42.567383	40-41
CTCGTAT	12550	0.0	42.284645	44-45
ATCTCGT	12570	0.0	42.009365	42-43
GTATGCC	12960	0.0	41.99639	46-47
>>END_MODULE